Acta Pharmaceutica Sinica B Volume 11, Number 12 Publications
Acta Pharmaceutica Sinica B (APSB) was founded with the aim of creating a high-level global forum focused on drug discovery and pharmaceutical research / application. APSB was included by Chemical Abstracts in 2011, accepted by PubMed Central in 2015, indexed by Science Citation Index in 2017 and has evolved into one of the most important international journals in the field of pharmaceutical sciences.
APSB is a monthly journal, in English, which publishes important original research articles, rapid communications and high-quality journals on recent advances in all fields of pharmaceutical sciences – including pharmacology, pharmacy, medicinal chemistry , natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics.
Special column on drug and chemical liver damage
This issue contains a special column entitled: Drug- and Chemical-Induced Liver Injury edited by James Luyendyk and Dafna Groeneveld, Department of Pathobiology and Diagnostic Investigation, Michigan State University East Lansing, MI, USA.
Articles of interest in this column include:
Dual role of p62 / SQSTM1 in the lesion and recovery phases of acetaminophen-induced liver damage in mice by Hui Qian, Qingyun Bai, XiaoYang et al. (https://doi.org/10.1016/j.apsb.2021.11.010). Overdose of acetaminophen (APAP) can induce liver damage and is the most common cause of acute liver failure in the United States. The authors of this article investigated the role of p62 / SQSTM1 (termed p62) in APAP-induced liver injury (AILI) in mice.
The key role of the gut-liver axis in hepatotoxicity and enterotoxicity induced by pyrrolizidine alkaloids by Yisheng He, Jiang Ma, Xiaoyu Fan et al. (https://doi.org/10.1016/j.apsb.2021.07.013). The authors of this article provide evidence for the mode of action of PA-induced enterotoxicity and stress the importance of intestinal barrier function in PA-induced liver injury.
Hepatotoxicity Reports in the FDA Adverse Event Reporting System Database: A Comparison of Drugs That Cause Damage Via Mitochondrial or Other Mechanisms by Payal Rana, Michael D. Aleo, Xuerong Wen and Stephen Kogut. (https://doi.org/10.1016/j.apsb.2021.05.028). Drug-induced mitochondrial toxicity (DILI) has been shown to play an essential role in various forms of DILI, particularly in idiosyncratic liver damage. This study examines reports of liver injury submitted to the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) for drugs associated with hepatotoxicity via mitochondrial mechanisms versus non-mitochondrial toxicity mechanisms.
Other articles in the special section on drug and chemical liver injury include:
Antonio Segovia-Zafra, Daniel E. Di Zeo-Sánchez, Carlos López-Gómez, Zeus Pérez-Valdés, … Marina Villanueva-Paz
Layla Shojaie, Myra Ali, Andrea Iorga, Lily Dara
Hartmut Jaeschke, Olamide B. Adelusi, Jephte Y. Akakpo, Nga T. Nguyen et al.
Regina D. Schnegelberger, Anna L. Lang, Gavin E. Arteel, Juliane I. Beier
Juliane I. Beier, Gavin E. Arteel
Gundala Venkata Naveen Kumar, Keito Hoshitsuki, Sanjay Rathod, Manda J. Ramsey et al.
Jian Jin, Banrida Wahlang, Monika Thapa, Kimberly Z. Head et al.
Melissa M. Clemens, Stefanie Kennon-McGill, Joel H. Vazquez, Owen W. Stephens et al.
Daniel Rizzolo, Bo Kong, Rulaiha E. Taylor, Anita Brinker et al.
Joseph L. Jilek, Kayla L. Frost, Kevyn A. Jacobus, Wenxi He et al.
Other articles published in the issue include:
Zinuo Chen, Ruikun Du, Jazmin M. Galvan Achi, Lijun Rong, Qinghua Cui
Zheng Su, Dian Xiao, Fei Xie, Lianqi Liu et al.
Meng Liu, Shan Gao, Reham M. Elhassan, Xuben Hou, Hao Fang
Zhihao Fu, Hongchuan Liu, Lan Wang, Chuanfei Yu et al.
Manni Wang, Siyuan Chen, Yuquan Wei, Xiawei Wei
Linglong Deng, Hannah Petrek, Mei-Juan Tu, Neelu Batra et al.
Yancheng Tang, Liming Wang, Tao Yi, Jun Xu et al.
Valeria Marrocco, Tuan Tran, Siying Zhu, Seung Hyuk Choi et al.
Huaqing Zheng, Xiaolong Li, Xin Zeng, Chengcui Huang et al.
Meijia Qian, Fangjie Yan, Weihua Wang, Jiamin Du et al.
Hua Sang, Jiali Liu, Fang Zhou, Xiaofang Zhang et al.
Ting Lei, Zhihang Yang, Xue Xia, Yuxiu Chen et al.
Na Kong, Xiaying Chen, Jiao Feng, Ting Duan et al.
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The Journal of Institute of Materia Medica, Chinese Academy of Medical Sciences and the Chinese Pharmaceutical Association.
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